Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Crest
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A bearing worn, not upon the shield, but usually above it, orseparately as an ornament for plate, liveries, and the like. It is arelic of the ancient cognizance. See Cognizance, 4.
Crest meaning & definition 1 of Crest.
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a hood in Vallejo, California...
Crest meaning & definition 2 of Crest.
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Country Club Crest Side of Vallejo, Ca. Home of the world renown Andre Hicks aka Mac Dre aka The Furley Ghost himself.
Crest meaning & definition 3 of Crest.
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clean up, straighten out, right what is wrong, Undo mess
Crest meaning & definition 4 of Crest.
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when a man ejeculates on a person without knowing and becomes hard on their clothing and makes it look like a crusty substance.
Crest meaning & definition 5 of Crest.
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You are getting a blowjob and just before you explode, you tell your partner to smile then you unload your cum all over their teeth!
Crest meaning & definition 6 of Crest.
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To sex someone, harder than usual, but not as hard as possible.
Crest meaning & definition 7 of Crest.
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Code word for a hot girl when you are staying at a campground.
Origin: You are standing outside your tent brushing your teeth and a girl walks by who is so hot that you accidentally squeeze out your tube of toothpaste.
Crest meaning & definition 8 of Crest.
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Crips
Rollin
East
Side
TerritoriesCrest meaning & definition 9 of Crest.
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a slang word, often used to replace leave
Derived from American Idol, as in Ryan Seacrest, as in 'Seacrest Out'. (what he says at the end of the show) Sometimes, but not necessarilly used by gaywads.
Crest meaning & definition 10 of Crest.
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descriptive word, replace any word in the english language
Crest meaning & definition 11 of Crest.
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Crest in Surfing. The highest point of a wave before it breaks.
Crest meaning & definition 12 of Crest.