Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Goop
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Very potent, sticky cannabis.
Goop meaning & definition 1 of Goop.
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a liquid drug that fucks you upp
Goop meaning & definition 2 of Goop.
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The excretion made by a vagina when the woman is being pleasured like never before. It is similar to elmers glue leaking out of the bottle.
Goop meaning & definition 3 of Goop.
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To cum inside something.
Goop meaning & definition 4 of Goop.
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a sloppy, flabby, loose vagina. often very disgusting.
Goop meaning & definition 5 of Goop.
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Goop or Goopin means to turn up, drink and have fun
Goop meaning & definition 6 of Goop.
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To refer towards someones intelligence which isnt quite up to par given the situation.
Goop meaning & definition 7 of Goop.
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A sometimes blue, almost always green goo-like substance that kicks ass.
A commonly used saying that expresses excitement or happiness when said in a high pitch.
Goop meaning & definition 8 of Goop.
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To unexpectedly poke someone in the lower stomach or kidney area with ones index and middle finger.
Goop meaning & definition 9 of Goop.
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1.)The Large underchin of [a human] being,
2.)When someone [cups] the [flabby],large underchin of a human being, and lets go.Goop meaning & definition 10 of Goop.
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any thick liquid or sticky substance
Goop meaning & definition 11 of Goop.