Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Wendigo
-
An unusual creature from Yukon myths, half phantom, half beast, embodying the dangers of Winter in the flesh. An elemental spirit of the wind and cold, it moves through the woods with preternatural stealth and speed, leaving hauntingly scorched trails of distantly spaced footprints in the snow.
Its attributed various powers, including flight, invisibility, the projection of illusions, and a keen tracking sense for its prey - typically unwary travellers, especially young and foolhardy ones.
The most common origin for a Wendigo is the consumption of human flesh during a harsh winter; this awakens a feral hunger that gradually transforms one into the monster. Intentional association with fell powers (bad medicine) can also achieve the same result.
The Wendigo has been made most famous by its use by Algernon Blackwood in his short story The Wendigo. Its since inspired a Marvel comics character by the same name and various movies and television shows.
Also a well-known knave from Gaia Online.
Wendigo meaning & definition 1 of Wendigo.
-
The soul of a cannibal doomed to wander the earth entirely famished and craving human flesh. They leave burning footprints in the snow.
Wendigo meaning & definition 2 of Wendigo.
-
A mythical creature that is created by cannibalism in Native American grounds because of a curse. Yes its also that thing from Until Dawn.
Wendigo meaning & definition 3 of Wendigo.
-
Democratic Senator and ex-First Lady Hillary Clinton
Wendigo meaning & definition 4 of Wendigo.
-
A person who is or looks like a prostitue
Wendigo meaning & definition 5 of Wendigo.
-
A [cannibal] [creature]
Wendigo meaning & definition 6 of Wendigo.
-
a [tall], [skinny], [man-eater]
Wendigo meaning & definition 7 of Wendigo.