Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Homegrown
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Refers to home-grown marijuana.
Homegrown meaning & definition 1 of Homegrown.
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1.homegrown a noun, meaning a video made independantly and or at home, usually involes skits, pranks, stunts and extreme sports
2.homegrown a noun, meaning weed grown at homeHomegrown meaning & definition 2 of Homegrown.
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Pornography posted on internet forums where the poster is the subject themselves. esp. on Something Awful.
Homegrown meaning & definition 3 of Homegrown.
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from your own garden:
Homegrown meaning & definition 4 of Homegrown.
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Grown or produced in ones own garden or country.
Homegrown meaning & definition 5 of Homegrown.
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