Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Dik dik
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The game 20 Questions definition of a penis.
Dik dik meaning & definition 1 of Dik dik.
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the cutest animal ever! looks like a mini deer but 100 times cuter.
featured in Madagascar 2.Dik dik meaning & definition 2 of Dik dik.
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Originated from the video game character dik dik van dik in ultimate muscle. Quite possibly the best phrase in human history. It should be said often and with enthusiasm.
Dik dik meaning & definition 3 of Dik dik.
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