Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Busty
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Female with large breasts, usually the cause of car accidents, neck cricks and walking into walls.
Busty meaning & definition 1 of Busty.
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Girl with big tits
Busty meaning & definition 2 of Busty.
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(Of a womans body) Large-[breast]ed. Very busty women are often [buxom], [plump], and [voluptuous] in body.
Men tend to like busty women more, and feel that theyve died and gone to heaven when they see a [lady] with breasts the size of [honeydew] melons.
Busty meaning & definition 3 of Busty.
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adj - boobs that are so big they look as though they will bust through the shirt
Busty meaning & definition 4 of Busty.
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A word you mistakenly type instead of busy when addressing an email to a predominantly female group of recipients. Followed by a tough climb down.
Busty meaning & definition 5 of Busty.
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in laguna beach,
- word used to describe someone who is not careful about theyre drug or alcohol usage
- used to describe a situation which can get you in trouble or in danger
- likely to get busted
Busty meaning & definition 6 of Busty.
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short for bustdown; a ho/slut who sleeps with a lot of different guys, especially ones in the same gang, crew, set, etc.
Busty meaning & definition 7 of Busty.
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A not so nice name to call someone. A childish rant.
Busty meaning & definition 8 of Busty.
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[Big tits], curvy [bodied] female usually associated with [latina] women
Busty meaning & definition 9 of Busty.
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something to sqeeze when bored, espesially [Dawns] [breast]. [woot].
Busty meaning & definition 10 of Busty.
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A busty woman has large breasts.
Busty meaning & definition 11 of Busty.
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A woman with big [breasts] that looks [petite], but is actually [skinny].
Busty meaning & definition 12 of Busty.