Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Derby
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The only City which is so boring and uninteresting that the first entries under its name are unrelated to the place.
A poor mans Nottingham which has an alarming affection for Sheep.
Derby meaning & definition 1 of Derby.
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a football match between two teams from the same city or area.
Derby meaning & definition 2 of Derby.
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A city that is mainly fields, only made into a city because it was [The Queen]s silver jubilee and they didnt have anything else to do.
Derby meaning & definition 3 of Derby.
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slang for a popular strain of Cannabis originating in the 1970s called Durban Poison (or Durban, named after the South African port city). As mentioned in the Puff Daddy
Derby meaning & definition 4 of Derby.
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A sly and polite way to say head. Derived from the derby style of tophats. You put tophats on your head...thus, they become equated.
Derby meaning & definition 5 of Derby.
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An ice cream in a cone which has been chocolate dipped
Derby meaning & definition 6 of Derby.
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noun, human [detritus], esp. with [perverse] connotations.
Singular and plural are identical denoting a substance, as with [water].
Phonetically it is a corrupted form of [debris] perhaps combined with [dirty], i.e. [debris] [dirty] = [derby].Derby meaning & definition 7 of Derby.
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The worst city in the world! But its located next to the best city aka nottingham. It has bad garages, Bad trafic and the worst football team known to man
Derby meaning & definition 8 of Derby.
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a sports event between teams in the same area:
Derby meaning & definition 9 of Derby.