Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Loony
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a person whos crazy
Loony meaning & definition 1 of Loony.
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short for [lunatic]. A [crazy] person. This term is derived from the phrase [crazy as a loon].
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in [Canada] this word denotes a 1 dollar coin that has a [loon] bird on one side. A [Canadian] 2 dollar coin, which has a [polar bear] on one side is called a [toony].
Loony meaning & definition 2 of Loony.
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Goofy, crazy.
I guess it could also mean like a loon (the bird), but what would that be saying?
Loony meaning & definition 3 of Loony.
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Another name for [Luna Lovegood] from Harry Potter. Its a nickname that she got from being so quirky.
Loony meaning & definition 4 of Loony.
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A Canadian dollar coin.
Loony meaning & definition 5 of Loony.
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Someone who thinks they are effected by the phases of the moon - especially a full moon
Loony meaning & definition 6 of Loony.
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Adjective; Crazy, Nutty or Psychotic
Used to describe someone when they are acting or saying something crazy or unbelievable.
Loony meaning & definition 7 of Loony.
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An alcoholic [pervert] with shit feet who [speaks] to himself who where’s a shirt to work and drinks [chicken soup]
Loony meaning & definition 8 of Loony.