Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Bun
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to bun, the smoking of marujana/ hashish, london uk dialect. derived from the word burn.
Bun meaning & definition 1 of Bun.
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fuck, forget about, damn
Bun meaning & definition 2 of Bun.
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To smoke ganja
Bun meaning & definition 3 of Bun.
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People in montreal often use the word Bun for smoking weed. Bunning=smoking weed.
Bun meaning & definition 4 of Bun.
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West Indian pronunciation of the word burn, often used in reference to smoking weed or if something is on fire
Bun meaning & definition 5 of Bun.
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n. A person (male or female) youre seeing/dating and have an affectionate relationship with. Not a one nighter or fuck buddy. Someone you dont mind hugging or kissing in public. Sometimes (in DC) used inter-changeably with boo.
v. To meet up with the aforementioned person and do warm fuzzy couple things, such as watch a movie and/or cuddle. To bun.Bun meaning & definition 6 of Bun.
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Someones butt, or rear end.
Bun meaning & definition 7 of Bun.
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A small cake, typically containing dried fruit.
Bun meaning & definition 8 of Bun.
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