Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Chiba
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Marijuana.
Chiba meaning & definition 1 of Chiba.
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A prefecture in Japan, across the Toyko bay from the capital.
Chiba meaning & definition 2 of Chiba.
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aka chiva, from Spanish for a female goat. On the East Coast, Chiba means marijuana. This is from Caribbean Spanish. On the West Coast and some parts of the Midwest, Chiba means heroin. The latter comes from the Mexican Spanish.
Chiba meaning & definition 3 of Chiba.
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Chiba is a portable mp3 player made by rio audio.
Chiba meaning & definition 4 of Chiba.
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misheard, the actual word is chiva. chiva is heroin. cheeba is not a word, disregard any definitions of cheeba.
Chiba meaning & definition 5 of Chiba.
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(n) Chiba is how retarded fucks spell the word cheeba. It is one of the better terms used to describe marijuana.
Chiba meaning & definition 6 of Chiba.
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an ugly girl...one not worth fucking
Chiba meaning & definition 7 of Chiba.
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A city in Japan, on the island of Honshu, east of Tokyo; population 910,142 (2007).
Chiba meaning & definition 8 of Chiba.
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