Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Azimuth
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Microsofts indication that youre not typing your CSS in the exact manner theyve intended.
Azimuth meaning & definition 1 of Azimuth.
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the position of an object in the sky, expressed as an angle related to a distance on the horizon of the Earth
Azimuth meaning & definition 2 of Azimuth.
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The direction of a celestial object from the observer, expressed as the angular distance from the north or south point of the horizon to the point at which a vertical circle passing through the object intersects the horizon.
Azimuth meaning & definition 3 of Azimuth.
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