Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Vasectomy
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To cut the tubes from a mans balls to his penis to prevent sperm from leaving the body.
Vasectomy meaning & definition 1 of Vasectomy.
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A surgery to render a man impotent; aka the gift that keeps on giving (literally and figuratively speaking)
Vasectomy meaning & definition 2 of Vasectomy.
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Devenomizing the Cobra
Vasectomy meaning & definition 3 of Vasectomy.
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When a man has unlimited [amo] but can only [shoot out] [blanks].
Vasectomy meaning & definition 4 of Vasectomy.
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The surgical cutting and sealing of part of each vas deferens, typically as a means of sterilization.
Vasectomy meaning & definition 5 of Vasectomy.
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