Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Twang
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To make your voice go high pitched all of a sudden, for a quick moment, then go back to regular sounding. a lot of old western music singers have this wonderful talent. also alex burrows on the Vancouver canucks has an uncontrollable twang.
Twang meaning & definition 1 of Twang.
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A taste similar to tang, but with a little more of a kick.
Twang meaning & definition 2 of Twang.
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a twitpic of your wang
Twang meaning & definition 3 of Twang.
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(noun) Its a sound that goes Twang.
(verb) To make something make the above sound.
(adj) Twangful.
Twang meaning & definition 4 of Twang.
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to be tweaked in the nads
Twang meaning & definition 5 of Twang.
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(verb)a slang word; a dance that is slutty and can be performed on a table or at a strip club, to move in a twerking manor
Twang meaning & definition 6 of Twang.
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to cancel an agreement.
Or more precisely, to state that you intend to do something, and then change ones mind. See also dingy
Twang meaning & definition 7 of Twang.
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- An accent nobody actually has.
- Yummy type of beer salt.
Twang meaning & definition 8 of Twang.
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The art of flicking, pulling or creating strain on someones body and releasing whilst it is strained. This creates the beautiful sensation of twanging
Twang meaning & definition 9 of Twang.
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A strong ringing sound such as that made by the plucked string of a musical instrument or a released bowstring.
Twang meaning & definition 10 of Twang.
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[Sike] or you [tought]...
Twang meaning & definition 11 of Twang.
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A spicy or Sour flavor of a woman’s genetalia
Twang meaning & definition 12 of Twang.
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to make a noise like that of a tight string being quickly pulled and released:
Twang meaning & definition 13 of Twang.