Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Misunderstanding
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Disagreement; difference of opinion; dissension;
quarrel.
Misunderstanding meaning & definition 1 of Misunderstanding.
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When two people try pursuing a relationship and run into a road bump where one knows whats going on and the other is confused and could jump to conclusions. A lot of relationships end like this sadly.
Misunderstanding meaning & definition 2 of Misunderstanding.
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If you dont know where you stand with somebody, Id say your moral compass isnt the only one that needs repairs.
Misunderstanding meaning & definition 3 of Misunderstanding.
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A failure to understand something correctly.
Misunderstanding meaning & definition 4 of Misunderstanding.
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When one person says or does something insulting or [hurtful] to another person and later avoids the [apology] by stating that the entire situation was simply a [misunderstanding].
Misunderstanding meaning & definition 5 of Misunderstanding.
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an occasion when someone does not understand something correctly:
Misunderstanding meaning & definition 6 of Misunderstanding.
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