Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Flat
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The name given to an apartment which you rent weekly or monthly.
The name given to someone who is not [cool] and is dull and boring
The name given to a woman with no or hardly any breasts.
Something which is level, does not decrease or increase.
The name given to something filled with air which is now de-flated.
Flat meaning & definition 1 of Flat.
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adj. Used to describe a person of the female sex as to having no breasts.
Flat meaning & definition 2 of Flat.
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Used to describe soda that has been left out too long or is old, thus losing its carbon-doxide infused goodness that we like to call fizz. It is not good. It makes people sad.
flats best friend and synonym is warm.
Flat meaning & definition 3 of Flat.
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tits that resemble tortillas
Flat meaning & definition 4 of Flat.
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an adjective used to describe a girl with no ass or tits.
Flat meaning & definition 5 of Flat.
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Small-breasted.
Flat meaning & definition 6 of Flat.
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something boring or tedious
Flat meaning & definition 7 of Flat.
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[Kirk]
Flat meaning & definition 8 of Flat.
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Short on [cash], running [low] on money, going [broke].
Flat meaning & definition 9 of Flat.
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Flat in American Football. The area of the field behind the line of scrimmage and between the sideline and the offensive line.
Flat meaning & definition 10 of Flat.