Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Leyland
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a town in lancashire, not excactly a chav hive, but has chavs, there is a cross near tesco that dates back to the saxon times, some sort of military training hut, and a continental market
Leyland meaning & definition 1 of Leyland.
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a boys name Leyand \l(e)-la-nd\ is pronounced LEE-land. It is of Old English origin, and its meaning is one who lives by unseeded land. Place name. Philantrophist Leland Stanford.
also the name lee as the same meaning
Leyland has 4 variant forms:Leyland meaning & definition 2 of Leyland.
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A Leyland is a small infected pustule resulting from having multiple sexually transmitted diseases. Oftentimes the semen from farm animals can compound the initial infection resulting in a Super Leyland which will then need to be lanced.
Leyland meaning & definition 3 of Leyland.
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A word used to describe someone who is high on drugs. The short for it is Ley.
Leyland meaning & definition 4 of Leyland.
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