Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Solera
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This really cool girl who lives in Kennesaw, Georgia with a smokin hot body. Her whole family has interesting names like this, but hers is far more awesomer than Ari or Durian. She has a new guy expressing their love to her about every other week, but she remains to keep it cool. She isnt a whore, which is kind of odd because if I looked like that, Id turn out to be the biggest slut this town has seen. Oh yeah and she lives down the street from Joe. And she lives across the street from these black people who stash [marijuana] in their floorboards. Issac lives down the street too, but hes Jewish so no one cares. Shes recieved many nicknames, the most popular being Fagnuleo(which somehow formed from disorting her last name). [Soleraitis] is a disease, meaning someone who has become very fond of Solera. All in all, Soleras pretty much amazing.
Solera meaning & definition 1 of Solera.