Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Feverish
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Having a fever; suffering from, or affected with, a
moderate degree of fever; showing increased heat and thirst; as, the
patient is feverish.
Feverish meaning & definition 1 of Feverish.
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a : [tending] to cause [fever]
b : having the symptoms of [a fever]
c : indicating or relating to feverFeverish meaning & definition 2 of Feverish.
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suffering from fever (= high body temperature) :
Feverish meaning & definition 3 of Feverish.
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Characterized by or displaying a frenetic excitement or energy.
Feverish meaning & definition 4 of Feverish.
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